Inactive

Michael E. DeBakey VA Medical Center 2002 Holcombe Blvd, Houston, TX 77030 580-23-1-026-0020 PURPOSE The Department of Veterans Affairs, NCO 16, Michael E. DeBakey VA Medical Center (MEDVAMC), 2002 Ho... Michael E. DeBakey VA Medical Center 2002 Holcombe Blvd, Houston, TX 77030 580-23-1-026-0020 PURPOSE The Department of Veterans Affairs, NCO 16, Michael E. DeBakey VA Medical Center (MEDVAMC), 2002 Holcombe Blvd., Houston, TX 77030, Rapid Analytical Chemistry section of Pathology and Laboratory Medicine Service (PLMS) is requesting a contract for Tacrolimus Laboratory Testing supplies. Tacrolimus is a macrolide antibiotic derived from the fungus Streptomyces tsukubaensis. Like cyclosporine, tacrolimus inhibits calcineurin to suppress T cells. Tacrolimus is metabolized by CYP3A4, thus its concentrations are affected by drugs that inhibit (calcium channel blockers, antifungal agents, some antibiotics, grapefruit juice) or induce (anticonvulsants, rifampin) this enzyme. Tacrolimus has a narrow therapeutic range, and adverse effects are common, particularly at high dose and concentrations, making therapeutic drug monitoring essential. The purpose is to procure multiple items and reagents required for Tacrolimus Laboratory testing which is critical for monitoring whole blood tacrolimus concentration during transplant therapy. QUANTITY Item # Description/Part Number* Qty Unit 23-278-445 QMS Tacrolimus Reagent R1 18mL, R2 12mL; Vendor Catalog # 10015556, Shelf Life 1Year, GSA# GS07F161BA, IMF# 61011 45 EA 23-278-444 QMS Tacrolimus Calibrator Set 6 levels, 4mL - Calibrator A, 2 mL - Calibrator B-F; Vendor Catalog # 10015573, Shelf Life 1Year, GSA# GS07F161BA, IMF# 61012 12 EA SALIENT CHARACTERISTICS Tacrolimus Laboratory testing reagents and supplies with deliveries that occur per the delivery schedule included with the acquisition packet. NOTE: Please award this as a C number Purchase Order because invoices need to be certified. DELIVERY LOCATION Michael E. DeBakey VA Medical Center ATTN: Bernita Hudson, Rapid Analytical Chemistry Supervisor 3rd Floor, Chemistry Lab, 3A-120 2002 Holcombe Blvd Houston, TX 77030 INVOICING/BILLING REQUIREMENTS The contractor shall submit invoices monthly in arrears covering the supply allocations delivered under this contract. The Contractor shall provide an itemized invoice to the required VA invoicing address or submission online through the appropriate website within 30 days of the end of each month that supply allocations were delivered. Invoices for allocations provided in the month of September must be received for certification no later than October 30th. The invoices shall contain the following information at a minimum: Contract Number Item Description Purchase Order Number Quantity Stock Number Price