AN11--Degenerative cervical myelopathy (DCM) multi-omics services
This amendment provides responses to offeror questions regarding the solicitation. The required RNA-seq sequencing depth is 6 Gb (150 million reads) per sample. For each of the 40 subjects, three specialized tubes will be collected: one PAXgene blood tube for RNA, and two plasma samples—one for metabolomics and one for proteomics—totaling 120 tubes. The required proteomics platform is DIA-based LC-MS/MS, not Olink. No budget figures or performance location are specified.