Inactive

PRE-SOLICITATION NOTICE – NOTICE OF INTENT NOI-NIAID-2176533 NAICS – 333314 This is a Notice of Intent, not a request for proposal. The National Institute of Allergy and Infectious Diseases (NIAID) of... PRE-SOLICITATION NOTICE – NOTICE OF INTENT NOI-NIAID-2176533 NAICS – 333314 This is a Notice of Intent, not a request for proposal. The National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health (NIH) intends to negotiate on an other than full and open competition basis with Discover Echo Inc to procure an Echo Revolve 4, model RVSF1000D, microscope and components for use in a BSL4 laboratory at Rocky Mountain Laboratories in Hamilton, MT. The Rocky Mountain Laboratories, of the National Institutes of Health (NIH), National Institute of Allergy and Infectious Disease (NIAID), Laboratory of Virology (LV) is requiring this model RVSF1000D microscope and components. LV scientists broadly study viral agents requiring high or maximum containment (biosafety level-2 to biosafety level-4) that cause viral hemorrhagic fevers, viral encephalitis, and certain respiratory diseases. These agents include filoviruses, bunyaviruses, arenaviruses, and coronaviruses (such as SARS-CoV-2 and MERS-CoV). This work employs investigations in cell culture; animal models, including nonhuman primates; reservoir species; and arthropod hosts in order to elucidate the viral pathogenesis, immune responses, molecular evolution, cellular and molecular biology, and vector-host interactions. Currently there are COVID-19 samples on premise ready for immediate processing. In the Molecular Pathogenesis Unit, work is being conducted with different styles of cell culture which require two different ways to view the health of cell monolayers; via upright or inversion. In years past this would be accomplished using two large-footprint microscopes, but with the invention of this microscope the capabilities of two microscopes have been combined into one. This microscope will serve the required purposes while allowing LV to maximize its minimal space for bench work and equipment. This microscope will be taken in to the BSL-4, and is the same as the LV microscope in the BSL-2. It is very difficult to train someone on equipment in the BSL-4 due to the containment restrictions so this will allow training to be done in the BSL-2 for staff that will ultimately use the BSL-4 location. By having the same style microscope, LV can more easily and safely train people on equipment at BSL-2 before use in the BSL-4. This exact model #RVSF1000D is only available directly from the manufacturer, Discover Echo Inc. Place of Performance: NIH/RML, 903 S. 4th Street, Hamilton, MT 59840, United States. FOB: Destination The statutory authority for this sole source requirement is 41 U.S.C. 1901 (a) (1) as implemented by FAR 13.106-1 only one responsible source and no other supply of service will satisfy agency requirements. THIS IS NOT A REQUEST FOR PROPOSAL. All responsible sources that could provide comparable services may submit a capability statement that will be considered by email (subject line to reference NOI-NIAID-23-2176533 to Dana Monroe at dana.monroe@nih.gov by 12:00pm EST May 30, 2023. All responses received by the closing date of this synopsis will be considered by the Government. A determination not to compete this requirement, based upon responses to this notice, is solely within the discretion of the Government.