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The Laboratory of Circuits, Synapses, and Molecular Signaling LCSMS studies fundamental issues of synaptic transmission, neuronal excitability, neuromodulation, and neural circuit activity using anima... The Laboratory of Circuits, Synapses, and Molecular Signaling LCSMS studies fundamental issues of synaptic transmission, neuronal excitability, neuromodulation, and neural circuit activity using animal models (principally, the mouse). A major line of research employs patch clamp electrophysiology, fluorescence imaging, and optogenetic stimulation in brain slices. For this research, the LCSMS requires two (2) low-noise patch clamp amplifiers, suitable for single channel recording and whole cell patch recording from neurons in brain slices. The amplifiers must also be compatible with extracellular recording. Please see Attachment 1 - Purchase Description for more information.