Inactive

This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR 12.6 as supplemented with additional information included in this notice. This announcement ... This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in FAR 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation and a separate written solicitation will not be issued. This solicitation number is NICHD-21-006 and is issued as a Request for Quotation (RFQ). The solicitation/contract will include all applicable provisions and clauses in effect through Federal Acquisition Circular 2020-09. The North American Industry Classification (NAICS) Code is 811219 with a size standard of $22m. However, this solicitation is not set aside for small business. This acquisition is being conducted using Simplified Acquisition Procedures in accordance with FAR Part 13. Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) intend to procure on a sole source basis from Sony Biotechnology Inc. – 1730 N. 1st Street – San Jose, CA 95112 97124 to provide a Fixed Priced Base Plus Three Options Periods Service Agreement/Extended Warranty (Base Year period of performance (POP) Dec 1, 2020 – Nov 30, 2021, 1st option period POP Dec 1, 2021 through Nov 30, 2022, the 2nd option period POP, Dec 1, 2022 through Nov 30, 2023 and the 3rd option period POP Dec 1, 2023 to Nov 30, 2024 ) for the following: Sony Cell Sorter, Model SH800SGP, Serial #0307001 – Quantity (1) EA Services to include but not limited to: 5-day Coverage –Monday through Friday (except Sony Biotechnology holidays) This Service Agreement covers the Sony Biotechnology instrument specified by serial number excluding computer workstation, options purchased separately from the instrument, and any third-party items (compressor, vacuum pump) sold at the time of purchase. The Service Agreement covers all labor, travel expenses, telephone support and parts, excluding some consumables. The Service Agreement includes: • One (1) Preventative Maintenance Inspection to be performed during the twelve-month period • Software revisions that are released during the term of the Service Agreement provided no hardware upgrades are required. • Unlimited telephone support for instruments and Sony Biotechnology proprietary software • Unlimited on-site service support if it is determined by Sony Biotechnology that on-site support is required Coverage Coverage hours are Monday through Friday from 9:00 AM to 5:00 PM local time, excluding Sony Biotechnology holidays. Response time For on-site support, our goal is for a qualified technician to arrive on-site within 72 hours of dispatch. The extended warranty for the SH800 cell sorter is needed for preventative maintenance and to ensure that any future issues are covered financially and will be repaired efficiently with minimal downtime. This sorter is heavily used by numerous NICHD labs and thus regular upkeep and maintenance is required to ensure that researchers can utilize this sorter for all current and future experiments. Sony Biotechnology Inc. (“Sony”) is the sole source provider of maintenance services for its products. Sony’s SH800SGP instrument/equipment is manufactured solely by Sony. The Equipment should only be repaired and serviced by a qualified Sony technician that is fully trained by Sony personnel. This specialized training is only offered to Sony’s direct employees. Furthermore, only Sony technicians have access to software updates and genuine Sony parts. As the original equipment manufacturer of the Equipment, Sony is the only company capable of providing all required resources to service the Equipment in a complete and professional manner. Due to the sensitive nature of the Equipment, it is imperative that the maintenance provider has access to the latest tools and materials required to keep the Equipment operating at optimum levels. In this case, Sony is the only company that can provide comprehensive maintenance services for the Equipment. The proposed contract action is for supplies or services for which the Government intends to solicit and negotiate with only one source under authority of the 41 U.S.C. 253(c) (1), FAR 6.302. Only one responsible source and no other supplies or services will satisfy agency requirements. The offeror must include a completed copy of the provision of FAR Clause 52.212-3, Offeror Representations and Certifications – Commercial Items with its offer. The provisions of FAR Clause 52.212-1 Instructions to Offerors – Commercial Items; FAR Clause 52.212-2, Evaluation – Commercial Items factors: technical capability to provide all products and service, price and past performance. Technical capability and past performance, when combined, are significantly more important than cost/price; FAR Clause 52.212-4, Contract Terms and Conditions – Commercial Items; and FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders – Commercial Items – Deviation for Simplified Acquisitions applies to this acquisition. Note to Contractor: The contractor shall provide a completed copy of FAR 52.204-24, "Representation Regarding Certain Telecommunications and Video Surveillance Services or Equipment" with their quote in response to this solicitation. The offeror must include their Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. The clauses are available in full text at http://www.acquisition.gov/far/. Interested vendors capable of furnishing the government with the products and services specified in this synopsis should submit a copy of their quotation to the below address or via email to robinsti@mail.nih.gov. All responsible sources who are certified by Sony Biotechnology Inc (Sony) as authorized third-party repair and service vendor may submit a proposal showing their capabilities and past performance from three separate customers (dated within the last 12 months of this notice) repairing this type of equipment/components. The vendors shall provide certification from original equipment manufacturer (OEM), Sony Biotechnology Inc (Sony) that they are authorized to perform these services and have access to OEM parts, software updates, supplies, continuous/updated training etc. Offers must also be accompanied by descriptive literature, delivery timeframe, warranties and/or other information that demonstrates that the offer meets all the foregoing requirements. Quotations will be due within fifteen calendar days from the publication date of this synopsis or by November 13, 2020 by 5:00 pm, EST. via email to robinsti@mail.nih.gov, ATTN: Tina Robinson, by the date and time mentioned above. The quotation must reference “Solicitation number” NICHD-21-006. Any questions must be sent via email to robinsti@mail.nih.gov and must include solicitation# NICHD-21-006 in the subject line of email. Faxed copies/responses will not be accepted. Note: In order to receive an award, contractor must be registered and have a valid all awards certification in the SAM database @www.sam.gov.

Inactive

INTRODUCTION THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A CONTRACT OR PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME). The Nat... INTRODUCTION THIS IS A PRE-SOLICITATION NON-COMPETITIVE (NOTICE OF INTENT) SYNOPSIS TO AWARD A CONTRACT OR PURCHASE ORDER WITHOUT PROVIDING FOR FULL OR OPEN COMPETITION (INCLUDING BRAND-NAME). The National Institutes of Health, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Office of Acquisitions (OA) on behalf of the on behalf of the National Institute of Digestive, Diabetes & Kidney Diseases intends to award a purchase order without providing for full and open competition (Including brand-name) to EDWAN LLC for lab work and research for the NIDDK Biomedical and Metabolic Imaging Branch. NORTH AMERICAN INDUSTRY CLASSIFICATION SYSTEM (NAICS) CODE The intended procurement is classified under NAICS code 541690 with a Size Standard of $15.00. REGULATORY AUTHORITY The resultant contract will include all applicable provisions and clauses in effect through the Federal Acquisition Circular (FAC) 2005-99. This acquisition is conducted under the procedures as prescribed in FAR subpart 13—Simplified Acquisition Procedures at an amount not exceeding the simplified acquisition threshold ($250,000). STATUTORY AUTHORITY This acquisition is conducted under the authority of 41 U.S.C. 253(c) under provisions of the statutory authority of FAR Subpart 6.302- FAR 6.302-1—Only one responsible source and no other supplies or services will satisfy agency requirements 41 U.S.C. 253(c)(1). PERIOD OF PERFORMANCE One Year upon Purchase Order Award Place of Performance National Institutes of Health National Institute of Digestive, Diabetes & Kidney Diseases 10 Center Drive Bethesda, MD 20892 DESCRIPTION OF REQUIREMENT Instrument Patients with rare genetic mutations such as hyper immunoglobulin E (Job's) syndrome (immune system and coronary arteries), Turner's syndrome (genetics and vascular disease), lipodystrophy (metabolic dysfunction and cardiovascular disease), or HIV infection (inflammation and coronary disease), share many of the metabolic and immunological dysregulations encountered in multi-organ disease subjects inclusive of atherogenesis. T-cell dysfunction mirrors that seen in obesity affecting leptin metabolism. Finally, it is well established that such subjects acquire accelerated atherosclerosis. Therefore, a goal has been to isolate and understand the effects of these defects and the early events that signal atherosclerosis. Taking advantage of the effects of deregulation of metabolism, inflammation and immunity that play a key role in multi-organ disease progression of atherosclerosis in obesity and metabolic syndrome requires an in-depth understanding of the molecular basis of inflammatory diseases and studying their associated pro-inflammatory cytokines. Specifically, understanding the initiating pathways of the immune system, such as the Toll-Like Receptors (TLRs) and the inflammasome, to determine effective therapies involved in the dysregulation of these inflammatory signals as a treatment approach to ameliorate atherosclerosis and obesity, diabetes and hereditary autoinflammatory diseases. Novel role for mitochondrial STAT3 has been implicated in autoinflammatory diseases with an underlying component of mitochondrial dysfunction, such as Type 2 diabetes and obesity among many other diseases. Therefore, a deeper understanding of the interplay between STAT3 and mitochondria creates a great advantage to developing therapeutic approaches to treat inflammatory diseases. Research endeavors will employ a combination of flow cytometry, cell imaging, proteomic and bioinformatic approaches to further dissect mechanisms involved in mitochondrial regulation of inflammatory diseases. The National Institutes of Health (NIH), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Biomedical and Metabolic Imaging Branch has a requirement to obtain services of a scientist with extensive expertise in innate immunology and hereditary autoinflammatory diseases with demonstrated understanding of, and ability to apply principles, concepts, practices and standards associated with patient sample testing in a laboratory setting. CLOSING STATEMENT This synopsis is not a request for competitive proposals. However, interested parties may identify their interest and capability to respond to this notice. Responses to this notice shall contain sufficient information to establish the interested parties’ bona-fide capabilities for fulfilling the requirement and include: descriptive literature, delivery timeframe, warranties and/or other information that demonstrates that the offer meets all the foregoing requirements, the prompt payment discount terms, the F.O.B. Point (Destination or Origin), the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.” A determination by the Government not to compete this proposed contract based upon responses to this notice is solely within the discretion of the Government. The information received will normally be considered solely for the purposes of determining whether to proceed on a non-competitive basis or to conduct a competitive procurement. All responses to this notice shall be submitted electronically by 9:00 am Eastern Standard Time, on Wednesday, December 4, 2019 to the Contract Specialist, Amber Harris, at amber.harris@nih.gov . Assessment of Capability Lowest Price Technically Acceptable