The project aims to acquire one laboratory microtome for preparing thin, reproducible tissue sections from paraffin-embedded specimens. It will support the Bladder Cancer Section’s research on mechanisms of resistance to antibody-drug conjugates in bladder tumors. A dedicated unit is needed to enable timely, consistent in-house sectioning and improve experimental reproducibility and workflow efficiency. The microtome must provide precise section thickness control, stable specimen orientation, a secure blade holder with safety features, and an ergonomic design for repeated use. Reliable mechanical performance is essential to produce intact, uniform sections for downstream staining, imaging, and quantitative analysis.