Inactive

This is a combined synopsis/solicitation (CSS) for commercial services prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This ... This is a combined synopsis/solicitation (CSS) for commercial services prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. The solicitation number is HHS-NIH-NIDA(AG)-RFP-20-75N95020R00013 and the solicitation is being issued as a request for proposals (RFP). This acquisition is for commercial services and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13—Simplified Acquisition Procedures; FAR Subpart 13.5— Simplified Procedures for Certain Commercial Items; and FAR Part 12—Acquisition of Commercial Items, and is not expected to exceed the simplified acquisition threshold. The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular 2020-04, dated January 15, 2020. The associated NAICS code for this requirement is 621511 with a small business size standard of $35 million. This requirement is being solicited as full and open with no set-aside restrictions. Background: The National Institute on Aging (NIA), one of the 27 Institutes and Centers of NIH, leads the federal government in conducting and supporting research on aging and the health and well-being of older people. The Institute seeks to understand the nature of aging and the aging process, and diseases and conditions associated with growing older, in order to extend the healthy, active years of life. Its mission is to support and conduct genetic, biological, clinical, behavioral, social, and economic research on aging, foster the development of research and clinician scientists in aging, provide research resources, and disseminate information about aging and advances in research to the public, health care professionals, and the scientific community among a variety of audiences. Purpose and Objectives: Metabolomic services are required for the project ‘Gut driven mechanisms of systemic inflammation during aging’. Metabolomics, the scientific study of identifying chemical fingerprints by characterizing metabolites, the small molecules of the product of metabolism is being increasingly used as a functional readout of the changes in the physiological state of the organisms. Project requirements: Tier 1 comprehensive metabolite assessment on serum and feces samples from mice is required. Tier 1 comprehensive metabolite assessment includes but is not limited to: precision estimation of short chain fatty acids, amino acid metabolites and glycolipid metabolites using advanced Mass Spectrometry technology. The estimation of these metabolites are important for the understanding of biology and biomarker discovery of the ongoing aging gut metabolism project. Deliverables: A relative concentration profile of all structurally named small molecule entities. A statistical analysis of the resulting data. An outline of the analytical methods. Access to the MetaboLync Client Portal. Additional matrix. Absolute quantitation for all specimens provided by the client. Analysis of lactic acid. A sample analysis report that includes a description for reference chemicals and matrices used during sample analysis, corresponding qc performance information and the data table with sample results. Anticipated period of performance: Anticipated period of performance is for seven (7) months after date of award. Other important considerations: Desired turnaround time for the deliverables is 8 weeks Place of Performance: The National Institute on Aging 251 Bayview Blvd Baltimore, MD 21224 Government Responsibilities: The following FAR provisions shall apply to this solicitation: 52.212-1, Instructions to Offerors—Commercial Items, 52.212-2, Evaluation--Commercial Items. Evaluation factors that will be used to evaluate the offer most advantageous to the Government, price and other factors considered, include ability to meet the technical requirements stated in this CSS and on basis of best value to the government. Technical and past performance, when combined, are significantly more important than cost or price. Offerors must include a completed copy of the provision at 52.212-3, Offeror Representations and Certifications Commercial Items, with their offer. The Clause at 52.212-4, Contract Terms and Conditions Commercial Items, applies to this acquisition and the Clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders Commercial Items applies to this acquisition. There are no additional contract requirement(s) or terms and conditions applicable to this acquisition. The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. Responses to this solicitation must include sufficient information to establish the interested parties’ bona-fide capabilities of providing the product or service. The price quote shall include: product name, product description, price, delivery time after receipt of samples and any other information or factors that may be considered in the award decision. In addition, the Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov.” A written notice of award or acceptance of an offer, mailed or otherwise furnished to the successful offeror within the time for acceptance specified in the offer, shall result in a binding contract without further action by either party. Before the offer’s specified expiration time, the Government may accept an offer (or part of an offer), whether or not there are negotiations after its receipt, unless a written notice of withdrawal is received before award. All responses must be received by February 13, 2020 at 4:00 pm Eastern Standard Time (EST) and must reference solicitation number HHS-NIH-NIDA(AG)-RFP-20-75N95020R00013. Responses may be submitted electronically to Eric McKay, eric.mckay@nih.gov. Fax responses will not be accepted.