The Delphi Program aims to develop modular wearable or ingestible sensors for continuous monitoring of biological markers like hormones and cytokines, using a chiplet-based architecture to reduce cost, size, and power consumption. A solution summary is due by April 8, 2026, at 5:00 PM ET, which is required to submit a proposal. The program focuses on creating dry chiplets for ultra-low power management and secure data communication, as well as wet biosensor chiplets for measuring low-concentration biochemical markers. These chiplets must be integrated into biocompatible, fully encapsulated packages that support durable, long-term operation in biological environments. No budget amounts or specific location for performance of services are mentioned in the description.

This DRAFT notice describes the Delphi Program's vision to develop low-cost, modular wearable or ingestible sensors for continuous monitoring of biological markers like hormones and cytokines. The program aims to leverage chiplet-based microelectronics to reduce cost and size while improving performance, focusing on three key technical areas: ultra-low power management chiplets, secure data communication chiplets, and new "wet" biosensor chiplets for direct biological interface. A final required component is the development of new biocompatible packaging strategies to protect the electronics in biological environments. The end goal is to create a system that enables early disease detection, safe home recovery monitoring, and precision therapy management.