This ARPA-H TIGAR Exploratory Topic seeks innovative technologies to enable temperature-flexible, long-term storage of complex biologics like tissues and organs, moving beyond strict cryogenic or controlled-temperature requirements. Proposed solutions should overcome current roadblocks using a combination of new materials, AI/ML, biological interventions, devices, or processing methods. The focus is on practical strategies that ensure safe storage across a range of environmental conditions and reduce logistical hurdles, preferably at easy-to-maintain, non-cryogenic temperatures. Innovations must have a clear deployment strategy for thick tissues, not just cellular-level advances. For updates and details, including Proposer's Day information, follow the provided ARPA-H initiative link.