Treating Hereditary Rare Diseases With In Vivo Precision Genetic Medicines (THRIVE)

Inactive
Notice ID:ARPA-H-SOL-25-122

This amendment summary clarifies several requirements for the THRIVE program proposal. Key changes include making cost share strongly encouraged instead of mandatory and removing the requirement for multi-party teaming. The proposal process now includes a required virtual PowerPoint presentation, with slides due by December 22, 2025, and presentations scheduled from January 5 to January 16, 2026. Several proposal volumes and sections, including the Cost Proposal and Administrative Requirements, have been revised, with some only required if a proposer is invited to negotiate. The Q&A deadline has been extended to October 30, 2025.