This is a Sources Sought Notice for market research only; no contract will be awarded from it. NIH/NICHD’s Section of Cell Cycle Regulation requires a brand-name Lonza 4D-Nucleofector System—Core Unit and X Unit with a one-year warranty extension (two years total)—or a functionally equivalent domestic system for genetic manipulation of mammalian cells. The system must support small-volume transfection, nucleic acid/CRISPR delivery, sensitive cell types, manufacturer software/protocols, and either full compatibility with existing Lonza consumables/workflows or demonstrated equivalent performance without protocol revalidation. Delivery, installation, and training for up to five NIH personnel must occur at NIH in Bethesda, MD (Building 49), with training within 30 days of installation and all work completed within a 12-month period of performance from award. Market research seeks qualified vendors, including small businesses and authorized Lonza distributors/resellers, with Buy American Act compliance information and optional non-binding ROM pricing.