NIH is seeking information from qualified small businesses and R&D firms, under NAICS 541714 with a 1,000-employee size standard, to support the operation, consolidation, and/or recompete of one or more NIH-funded biorepositories beginning in FY 2028, including the NIDA Center for Genetic Studies and the NBDC Biobank supporting the ABCD and HBCD studies. The scope includes secure sample management and storage for at least 3,500,000 biospecimens, chain-of-custody, distribution, SOPs, and curation/harmonization of associated clinical and phenotypic data. Required laboratory capabilities include molecular biology, CLIA status, high-throughput genotyping/sequencing, mass spectrometry, advanced genomic and cellular techniques, histopathology, and primary cell banking. Informatics requirements include biorepository web portals, databases, APIs, secure interoperable data exchange, FISMA-level ATO compliance, and collaboration with NIH Data Centers and study teams. Capability statements should demonstrate relevant experience, personnel, facilities, and subcontractor collaborations; this notice is for market research only and does not commit the Government to award a contract.

NIH seeks capability statements from qualified small businesses to provide biobanking, laboratory analytics, and associated informatics services supporting NIH biorepositories, including the NIDA Center for Genetic Studies, NBDC Biobank, ABCD Study, and HBCD Study. The scope covers secure storage and management of at least 3,500,000 biospecimens, chain-of-custody, sample distribution, collection kits and training, SOPs, LIMS/relational databases, data harmonization, and transfers to controlled-access repositories. Required laboratory capabilities include molecular biology, quality control, CLIA status, high-throughput genomics/sequencing, proteomics/metabolomics, iPSC/neural stem cell generation, CRISPR editing, and FFPE tissue analysis. Informatics requirements include web portal development/maintenance, APIs, FISMA/NIH-compliant ATO security, interoperable data exchange, and advanced capabilities such as homomorphic encryption and distributed learning. Respondents must demonstrate relevant experience, personnel, facilities, and ability to collaborate with NIH Data Centers and study teams; this notice is for market research only, no award will result, and the applicable NAICS is 541714 with an SBA size standard of 1,000 employees or fewer.