Preclinical Medications Discovery and Abuse Liability Testing
This is a Sources Sought Notice for market research, not a solicitation, to identify qualified organizations capable of performing preclinical medications discovery and abuse liability testing in rodents for NIDA’s Addiction Treatment Discovery Program. The work involves evaluating potential pharmacotherapies for substance use disorders and generating abuse liability data for DEA drug scheduling, requiring in-house capability for specific in vivo pharmacology studies. Organizations must demonstrate experience with intracranial self-stimulation, withdrawal state assays, and operant responding procedures, as well as the ability to obtain DEA registration for Schedule I-V substances and comply with NIH animal care standards. The applicable NAICS code is 541715 with a size standard of 1,000 employees, and responses are due by June 12, 2026, at 5:00 PM Eastern Time. No budget amount or performance location is specified in the notice.