NIH intends to issue a sole-source, Firm-Fixed-Price Purchase Order to 10x Genomics for GEM-X Single Cell 5’ Gene Expression Kits and companion reagents, including specified GEM-X Universal 5’ Gene Expression v3 kits, Chromium GEM-X Single Cell 5’ Chip Kits v3, and Dual Index Kit TT Set A kits. The products are proprietary to 10x Genomics and are required to maintain compatibility with an existing 10x Genomics assay workflow and previously collected data. The reagents will support single-cell/single-nucleus gene expression profiling across approximately 96 individuals, complementing matched-participant data and aiding research into molecular risk factors, regulatory mechanisms, and therapeutic targets for cardiometabolic diseases. Although this is not a request for competitive quotations,