NINDS requires a 12-month subscription to the Illumina DRAGEN GCP Level 4 platform to process about 1,300,000 GB of whole-genome sequencing data from 10,000 human genomes. The platform must support graph-based alignment to hg38 and detect SNVs, indels, structural variants, copy number variants, and repeat expansions. It must be compatible with Illumina-generated data and existing DRAGEN-processed datasets. The contractor must provide access and operational availability sufficient to analyze all 10,000 genomes over the 12-month performance period.