Evaluation of a Lead NNMT Inhibitor in Humanized M
This is a notice of intent to award a non-competitive firm-fixed-price contract to GemPharmatech LLC, located in San Diego, California, for services related to a humanized nicotinamide N-methyltransferase (hNNMT) mouse model. The vendor is the only known source because it developed the model under prior NIH-funded work and maintains the necessary breeding resources. The requirement is justified because the NIH’s lead NNMT inhibitor shows lower activity against mouse NNMT, so evaluation in humanized mice is needed. The associated NAICS code is 541714 with a 1,000-employee size standard, and the requirement is not set aside for small business. The acquisition will not exceed the simplified acquisition threshold, though no specific dollar amount is provided.