This is a pre-solicitation notice of intent to award a non-competitive, brand-name contract to Nikon Instruments Inc. for a Nikon NSPARC detector upgrade to an existing Nikon AXR confocal microscope system supporting NIH/NICHD advanced biological imaging. The procurement is conducted under FAR Part 13 Simplified Acquisition Procedures, with an estimated value not exceeding the simplified acquisition threshold of $350,000. The upgrade is intended to improve imaging sensitivity, spatial resolution, and super-resolution performance while minimizing photobleaching and phototoxicity. Interested parties may submit a capability statement, technical proposal, and cost-price proposal, but the Government will determine whether to proceed non-competitively or competitively. This synopsis is not a request for competitive proposals.