The National Institutes of Health (NIH) seeks to acquire a state-of-the-art laser-scanning microscope system with Confocal, 3D-STED, FLIM, and Spectral Multiplexing imaging capabilities to replace a 12-year-old instrument at its Bethesda, MD campus. The system must include a white light laser, prism-based spectral detection, and support for imaging 15 or more fluorescent colors per sample. Performance of services, including delivery, installation, and training, will occur at the NIH main campus in Bethesda, MD. The government intends to award a Firm-Fixed-Price Purchase Order based on best value, evaluating technical acceptability, past performance, and price. Quotations are due by July 31, 2026, at 11:00 AM Eastern Time.