Inactive

This service should provide the following deliverables: 1. Properly formulate the compound for IV, IP and PO administration to mice in 3, 10 and 30 mg/kg concentrations respectively. 2. Run a mouse PK... This service should provide the following deliverables: 1. Properly formulate the compound for IV, IP and PO administration to mice in 3, 10 and 30 mg/kg concentrations respectively. 2. Run a mouse PK study in B57BL6 mice for the compounds at 3, 10 and 30 mg/kg concentrations, analyzing heart, brain, lung, plasma and liver. 3. For each compound dose, complete PK analysis at 6 time points through 24 hours with n=6 in tissues of interest: plasma, bone, liver, heart, brain.