Inactive

This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcem... This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotes are being requested and a written solicitation will not be issued. The solicitation number is 75N95023Q00334 and the solicitation is issued as a request for quotation (RFQ). The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) Number 2023-04, with effective date of June 2, 2023. The associated NAICS code is 334516 and the small business size standard is 500 employees. This requirement is full and open with no set-aside restrictions. This requirement is for the following items: ZEISS LSM900 AND 980 SYSTEMS OR EQUAL Generic Name of Product: confocal laser scanning microscope system and multi-photon scanning system Salient Characteristics: The specific salient characteristics/required features, product specifications and packaging for this acquisition are specified in the attached Purchase Description. The Government anticipates award of a firm fixed-price order for this acquisition, and the anticipated delivery date is 16 weeks after receipt of order (ARO). Delivery will be f.o.b. destination. The place of delivery and acceptance will be ATTN: Lisa Long NATIONAL INSTITUTE OF HEALTH 35 CONVENT DRIVE BLDG 35, BETHESDA MAIN CAMPUS/ 1B1004 BETHESDA, MD 20892 Email - lisa.long@nih.gov The provision at FAR 52.252-1, Solicitation Provisions Incorporated by Reference (Feb 1998), applies to this acquisition. This solicitation incorporates one or more solicitation provisions by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. The offeror is cautioned that the listed provisions may include blocks that must be completed by the offeror and submitted with its quotation or offer. In lieu of submitting the full text of those provisions, the offeror may identify the provision by paragraph identifier and provide the appropriate information with its quotation or offer. Also, the full text of a solicitation provision may be accessed electronically at these addresses: https://www.acquisition.gov/browse/index/far https://www.hhs.gov/grants/contracts/contract-policies-regulations/hhsar/index.html (End of provision) The following provisions apply to this acquisition and are incorporated by reference: FAR 52.204-7, System for Award Management (Oct 2018) FAR 52.204-16, Commercial and Government Entity Code Reporting (Aug 2020) FAR 52.211-6, Brand Name or Equal (Aug 1999) FAR 52.212-1, Instructions to Offerors-Commercial Products and Commercial Services (Mar 2023) FAR 52.212-3, Offeror Representations and Certifications-Commercial Products and Commercial Services (Dec 2022) FAR 52.225-6, Trade Agreements Certificate (Feb 2021)> HHSAR 352.239-73, Electronic and Information Technology Accessibility Notice (December 18, 2015) The clause at FAR 52.252-2, Clauses Incorporated by Reference (Feb 1998), applies to this acquisition. This contract incorporates one or more clauses by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. Also, the full text of a clause may be accessed electronically at these addresses: https://www.acquisition.gov/browse/index/far https://www.hhs.gov/grants/contracts/contract-policies-regulations/hhsar/index.html (End of clause) The following clauses apply to this acquisition and are incorporated by reference: FAR 52.204-13, System for Award Management Maintenance (Oct 2018) FAR 52.204-18, Commercial and Government Entity Code Maintenance (Aug 2020) FAR 52.212-4, Contract Terms and Conditions—Commercial Products and Commercial Services (Dec 2022). Addendum to this FAR clause applies to this acquisition and is attached. HHSAR 352.222-70, Contractor Cooperation in Equal Employment Opportunity Investigations (December 18, 2015) FAR 52.212-4, Contract Terms and Conditions--Commercial Items (Nov 2021). Addendum to this FAR clause applies to this acquisition and is attached. HHSAR 352.239-74, Electronic and Information Technology Accessibility (December 18, 2015) The following provisions and clauses apply to this acquisition and are attached in full text. Offerors MUST complete the provisions at 52.204-24 and 52.204-26 and submit completed copies as separate documents with their proposal. FAR 52.204-24 Representation Regarding Certain Telecommunications and Video Surveillance Services or Equipment (Nov 2021) FAR 52.204-26 Covered Telecommunications Equipment or Services-Representation (Oct 2020) FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders--Commercial Items (Mar 2023) NIH Invoice and Payment Provisions The provision at FAR clause 52.212-2, Evaluation – Commercial Items (Nov 2021), applies to this acquisition. (a) The Government will award a contract resulting from this solicitation to the responsible offeror whose offer conforming to the solicitation will be most advantageous to the Government, price and other factors considered. The following factors shall be used to evaluate quotes: 1. Price 2. Technical acceptability 3. Warranty 4. Customer Service and Training Availability 5. Delivery Terms Technical acceptability and Price, when combined, are (1) significantly more important than the remaining factors. The Offerors must include a completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications—Commercial Products and Commercial Services (Dec 2022), with its offer. If the offeror has completed FAR clause 52.212-3 at www.sam.gov, then the offeror does not need to provide a completed copy with its offer. The clause at FAR 52.212-4, Contract Terms and Conditions-Commercial Items (Nov 2021), applies to this acquisition. Addendum to this FAR clause applies to this acquisition and is attached. There are no additional contract requirement(s) or terms and conditions applicable to this acquisition The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. Responses to this solicitation must include sufficient information to establish the interested parties’ bona-fide capabilities of providing the product or service. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s), product description, and any other information or factors that may be considered in the award decision. Such factors may include: past performance, special features required for effective program performance, trade-in considerations, probable life of the item selected as compared with that of a comparable item, warranty considerations, maintenance availability, and environmental and energy efficiency considerations. Respondents proposing on an equal product of the brand-name product specified in this announcement must provide, as part of their response: (a) product, catalog, model, and/or part number(s); (b) product description; (c) all relevant information and documentation that the item(s) offered meets the salient physical, functional, or performance characteristics as specified in the purchase description; quantity; estimated price or cost; shipping, handling, and/or installation charges; and delivery date after receipt of order. The Unique Entity ID from SAM.gov, the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. All questions must be received by 12:00 p.m., Eastern Daylight/Standard Time, on 14, August , 2023, and reference Solicitation Number 75N95023Q00334. Questions may be submitted electronically to W Terry, Contract Specialist, at jw.terry@nih.gov. All quotations must be received by5:00 p.m., Eastern Daylight/Standard Time, on 15, August , 2023, and reference Solicitation Number 75N95023Q00334. Responses must be submitted electronically to JW Terry, Contract Specialist, at jw.terry@nih.gov. Fax responses will not be accepted.

Inactive Total Small Business Set-Aside (FAR 19.5)

The Dendrite Morphogenesis and Plasticity Section (DMPU) Section of the National Institute of Neurological Disorders and Stroke (NINDS) is seeking Capability Statements from Small Business organizatio... The Dendrite Morphogenesis and Plasticity Section (DMPU) Section of the National Institute of Neurological Disorders and Stroke (NINDS) is seeking Capability Statements from Small Business organizations under the North American Industry Classification System (NAICS) code 334516 that are manufacturers of confocal laser scanning microscope systems designed for imaging stained tissue and live tissue. This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement. This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement, to determine the method of acquisition and availability of domestic sources manufactured in the United States in sufficient and reasonably available commercial quantities and of satisfactory quality. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. Only Small businesses are encouraged to respond. For equipment/supply requirements, responses must include the place of manufacturing (i.e., address if supply/equipment is a domestic end product and include country of manufacture). For equipment/supply requirements, small businesses must also address the size status of the manufacturer under the applicable NAICS code (i.e., address Non-Manufacturer Rule). BACKGROUND INFORMATION AND OBJECTIVE: Dendrite Morphogenesis and Plasticity Section( DMPU) is a section of NIH/NINDS. Applying the Drosophila larval visual circuit, DMPU investigates the structural and functional plasticity change to find the mechanisms underlying the neurolonal development. DMPU needs to perform large-scale genetic screens on drosophila, with the aid of a confocal system, to take high-quality images to determine the dendrite morphology change at the cell level. Furthermore, analyze these candidate genes using in vivo live imaging with a multiphoton scanning system. The primary approach is to understand the molecular path to regulate dendrite morphogenesis and structural plasticity and learn the consequent function change due to deficits on homeostatic neuronal plasticity. The confocal microscope system described above will allow the DMPU to screen large scale genetically modified drosophila containing fluorescent reporters to learn certain gene functions and lively tracing fluorescent signal movement in larva brain. REQUIREMENT: Two Confocal Laser Scanning Microscope Systems NINDS/DMPU requires two Confocal Microscope Imaging Systems with the following properties and characteristics: Salient Characteristics: Essential features of the microscope systems must include: 1. Must configure to our existing 680-1080 Chameleon Vision laser 2. Have 405/488/561/639nm Visible lasers and multitrack imaging ability without channel cross-tal, by linewise or framewise switching of the laser excitation line. 3. Could excite multiphoton laser and detect dual channel imaging simultaneously 4. Distinguish between fluorophores with overlapping emission spectra 5. Multiple Objectives: 5x, 10x, 20x, 40x, 60x Objectives 6. High-performance microscopy camera with high speed and high resolution 7. Provide personalized and professional customer service and training 8. One laser microscope must also include the following: 9. Consists of 3 calibrated and linearized detectors. 10. Flexible multi-channel configuration utilizing the combination of prisms and plates 11. Sequential 3 detector spectral acquisition with 9.7nm spectral resolution for a full spectral scan. 12. Photon counting imaging mode allows the system to distinguish the arrival of single photons tens of times during pixel dwell time as an image is scanned (The red-cooled PMTs are run at 15MHz). 13. The TwinGate main beamsplitter utilizing 2 separate 13 position MBS wheels allowing up to 50 different laser combinations while maintaining a typical laser suppression of OD 7 or greater. 14. The highly efficient holographic grating leads to an even spectral dispersion over the entire visual spectral range (380-750 nm). Grating utilizes a 'spectral recycling loop' to recover non-separated light, redirecting it onto the holographic grating for optimum sensitivity. 15. The other laser microscope must also include the following: 16. With 2 calibrated and linearized MA PMT (Multi Alkali Photomultiplier tube) detectors and one 32 channel Other Requirements: The vendor shall provide an Original Equipment Manufacturer (OEM) certified technician to perform the setup and installation of the equipment and provide the initial training. One year of full-service maintenance/warranty is required. Anticipated Delivery Date: The equipment shall be delivered within 16 weeks ARO. Delivery must be Freight on Board (FOB) Destination and include inside delivery. Other important considerations: In case domestic sources are available and capable of fulfilling the Government's need, and a future solicitation is published, the Government will use evaluation preferences in accordance with FAR 25. INSTRUCTIONS: Companies that believe they possess the capabilities to provide the required product should submit documentation of their ability to meet each requirement to the Contracting Officer. The capability statement must specifically address each of the requirements separately. Additionally, the capability statement should include: 1) the total number of employees, 2) the professional qualifications of personnel as it relates to the requirements outlined, 3) any contractor GSA Schedule contracts and other government-wide acquisition contracts (GWACs) by which all of the requirements may be met, if applicable, and 4) any other information considered relevant to this program. Capability statements must include the Company Name, Unique Entity ID from SAM.gov, Physical Address, and Point of Contact Information. The response must consist of the respondent's technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses. Interested companies must identify their type of business, applicable North American Industry Classification System (NAICS) Code, and size standards per the Small Business Administration. When submitting this information, please reference the solicitation notice number. The Government requests that no proprietary or confidential business data be submitted in response to this notice. However, responses that indicate the information therein is proprietary will be properly safeguarded for Government use only. Capability statements must include the name and telephone number of a point of contact having the authority and knowledge to discuss responses with Government representatives. Capability statements in response to this market survey that does not provide sufficient information for evaluation will be considered non-responsive. Any other specific and relevant information about this particular area of procurement that would improve our consideration and evaluation of the information presented is desirable. Documentation may include, but not be limited to, contracts, both Government and commercial the organization performed, references, i.e., names, titles, telephone numbers, and any other information serving to document the organization's capability, e.g., awards, commendations, etc. One (1) copy of the response is required and must be in Microsoft Word or Adobe PDF format using 11-point or 12- point font, 8-1/2" x 11" paper size, with 1" top, bottom, left and right margins, and with single or double spacing. The information submitted must be in an outline format that addresses each of the elements of the requirement and in the capability statement paragraphs stated herein. A cover page and an executive summary may be included but are not required. All responses to this notice must be submitted electronically to the Contract Specialist and Contracting Officer. Facsimile responses are NOT accepted. The response must be submitted to JW Terry, Contract Specialist, at jw.terry@nih.gov. Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or pay for the information provided in response. The Government reserves the right to use the information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is not obligated to acknowledge receipt of the information received or provide feedback to respondents concerning any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published on www.sam.gov. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).”

Inactive

The Dendrite Morphogenesis and Plasticity Section (DMPU) Section of the National Institute of Neurological Disorders and Stroke (NINDS) is seeking Capability Statements from all manufacturers of confo... The Dendrite Morphogenesis and Plasticity Section (DMPU) Section of the National Institute of Neurological Disorders and Stroke (NINDS) is seeking Capability Statements from all manufacturers of confocal laser scanning microscope systems designed for imaging stained tissue and live tissue. This is a Sources Sought notice. This is not a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement. This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement, to determine the method of acquisition and availability of domestic sources manufactured in the United States in sufficient and reasonably available commercial quantities and of satisfactory quality. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. Small businesses are encouraged to respond. For equipment/supply requirements, responses must include the place of manufacturing (i.e., address if supply/equipment is a domestic end product and include country of manufacture). For equipment/supply requirements, small businesses must also address the size status of the manufacturer under the applicable NAICS code (i.e., address Non-Manufacturer Rule). BACKGROUND INFORMATION AND OBJECTIVE: Dendrite Morphogenesis and Plasticity Section( DMPU) is a section of NIH/NINDS. Applying the Drosophila larval visual circuit, DMPU investigates the structural and functional plasticity change to find the mechanisms underlying the neurolonal development. DMPU needs to perform large-scale genetic screens on drosophila, with the aid of a confocal system, to take high-quality images to determine the dendrite morphology change at the cell level. Furthermore, analyze these candidate genes using in vivo live imaging with a multiphoton scanning system. The primary approach is to understand the molecular path to regulate dendrite morphogenesis and structural plasticity and learn the consequent function change due to deficits on homeostatic neuronal plasticity. The confocal microscope system described above will allow the DMPU to screen large scale genetically modified drosophila containing fluorescent reporters to learn certain gene functions and lively tracing fluorescent signal movement in larva brain. REQUIREMENT: Two Confocal Laser Scanning Microscope Systems NINDS/DMPU requires two Confocal Microscope Imaging Systems with the following properties and characteristics: Salient Characteristics: Essential features of the microscope systems must include: Must configure to our existing 680-1080 Chameleon Vision laser Have 405/488/561/639nm Visible lasers, and with multitrack imaging ability without channel cross-talk, by linewise or framewise switching of the laser excitation line. Could excite multiphoton laser and detect dual channel imaging simultaneously Distinguish between fluorophores with overlapping emission spectra Multiple Objectives: 5x, 10x, 20x, 40x, 60x Objectives High-performance microscopy camera with high speed and high resolution Provide personalized and professional customer service and training One laser microscope must also include the following: Consists of 3 calibrated and linearized detectors. Flexible multi-channel configuration utilizing the combination of prisms and plates Sequential 3 detector spectral acquisition with 9.7nm spectral resolution for a full spectral scan. Photon counting imaging mode allows for the system to distinguish the arrival of single photons many tens of times during pixel dwell time as an image is scanned (The red-cooled PMTs are run at 15MHz). The TwinGate main beamsplitter utilizing 2 separate 13 position MBS wheels allowing up to 50 different laser combinations while maintaining a typical laser suppression of OD 7 or greater. The highly efficient holographic grating leads to an even spectral dispersion over the entire visual spectral range (380-750 nm). Grating utilizes a 'spectral recycling loop' to recover non-separated light, redirecting it onto the holographic grating for optimum sensitivity. The other laser microscope must also include the following: With 2 calibrated and linearized MA PMT (Multi Alkali Photomultiplier tube) detectors and one 32 channel GaAsP PMT Other Requirements: The vendor shall provide an Original Equipment Manufacturer (OEM) certified technician to perform the setup and installation of the equipment and provide the initial training. One year of full-service maintenance/warranty is required. Anticipated Delivery Date:The equipment shall be delivered within 16 weeks ARO. Delivery must be Freight on Board (FOB) Destination and include inside delivery. Other important considerations: In case domestic sources are available and capable of fulfilling the Government's need, and a future solicitation is published, the Government will use evaluation preferences in accordance with FAR 25. INSTRUCTIONS: Companies that believe they possess the capabilities to provide the required product should submit documentation of their ability to meet each requirement to the Contracting Officer. The capability statement must specifically address each of the requirements separately. Additionally, the capability statement should include 1) the total number of employees, 2) the professional qualifications of personnel as it relates to the requirements outlined, 3) any contractor GSA Schedule contracts and other government-wide acquisition contracts (GWACs) by which all of the requirements may be met, if applicable, and 4) any other information considered relevant to this program. Capability statements must include the Company Name, Unique Entity ID from SAM.gov, Physical Address, and Point of Contact Information. The response must consist of the respondent's technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses. Interested companies must identify their type of business, applicable North American Industry Classification System (NAICS) Code, and size standards per the Small Business Administration. When submitting this information, please reference the solicitation notice number. The Government requests that no proprietary or confidential business data be submitted in response to this notice. However, responses that indicate the information therein is proprietary will be properly safeguarded for Government use only. Capability statements must include the name and telephone number of a point of contact having the authority and knowledge to discuss responses with Government representatives. Capability statements in response to this market survey that do not provide sufficient information for evaluation will be considered non-responsive. Any other specific and relevant information about this particular area of procurement that would improve our consideration and evaluation of the information presented is desirable. Documentation may include, but not be limited to, contracts, both Government and commercial the organization performed, references, i.e., names, titles, telephone numbers, and any other information serving to document the organization's capability, e.g., awards, commendations, etc. One (1) copy of the response is required and must be in Microsoft Word or Adobe PDF format using 11-point or 12-point font, 8-1/2" x 11" paper size, with 1" top, bottom, left and right margins, and with single or double spacing. The information submitted must be in an outline format that addresses each of the elements of the requirement and in the capability statement paragraphs stated herein. A cover page and an executive summary may be included but are not required. All responses to this notice must be submitted electronically to the Contract Specialist and Contracting Officer. Facsimile responses are NOT accepted. The response must be submitted to JW Terry, Contract Specialist, at jw.terry@nih.gov. Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or pay for the information provided in response. The Government reserves the right to use the information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is not obligated to acknowledge receipt of the information received or provide feedback to respondents concerning any information submitted. After a review of the responses received, a pre-solicitation synopsis and solicitation may be published on www.sam.gov. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s)."