Inactive

STREAMLINED SOLICITATION FOR COMMERCIAL ITEMS COMPETITIVE COMBINED SYNOPSIS / SOLICITATION Classification code: 66 Title: Thermo Fisher Scientific Falcon 4i Direct Electron Detector or Equal (i) This ... STREAMLINED SOLICITATION FOR COMMERCIAL ITEMS COMPETITIVE COMBINED SYNOPSIS / SOLICITATION Classification code: 66 Title: Thermo Fisher Scientific Falcon 4i Direct Electron Detector or Equal (i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. (ii) The solicitation number is 75N95023Q00079 and the solicitation is issued as a Request for Quotation (RFQ). This acquisition is for a commercial item or service and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13—Simplified Acquisition Procedures; and FAR Part 12—Acquisition of Commercial Items and is not expected to exceed the simplified acquisition threshold. (iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) Number 2023-03, with effective date 04/26/2023. (iv) The associated NAICS code 334516 Analytical Laboratory Instrument Manufacturing and the small business size standard is 1,000 employees. This requirement is full and open with no set-aside restrictions. (v) The purpose of this requirement is to procure a quantity of one (1) Thermo Fisher Scientific Falcon 4i Direct Electron Detector or Equal for the National Institute of Neurological Disorders and Stroke (NINDS). This system is needed to allow NINDS researchers and scientists to conduct its research by collecting more micrographs in the unit time for higher detective quantum efficiency (DQE), efficient lossless data compression, shorter exposure time and faster scanning rate that further optimize productivity for 200kV and 200kV cryoelectron microscopy (cryo-EM). For complete details and specifications, refer to the Purchase Description (See Attachment 1). (vi) Price Schedule Line Item: 0001 Item: Thermo Fisher Scientific Falcon 4i Direct Electron Detector Quantity: One (1) Total Price: $__________ OR Line Item: 0001A Item: Equal Product Equipment Name__________ Quantity: One (1) Total Price: $__________ Total Price: $__________ (vii) The Government intends to issue a firm-fixed price purchase order. The Contractor shall deliver and install the equipment to the NIH Delivery Address in Bethesda, Maryland within 120-180 days after receipt of order (ARO). Delivery will be f.o.b. destination. The place of delivery, installation and acceptance is: NINDS Cryo-EM Core Facility Bldg. 35A / Rm BD-918B 35A Convent Drive Bethesda, MD 20892 (viii) FAR 52.252-1 Solicitation Provisions Incorporated by Reference (FEB 1998) This solicitation incorporates one or more solicitation provisions by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. The offeror is cautioned that the listed provisions may include blocks that must be completed by the offeror and submitted with its quotation or offer. In lieu of submitting the full text of those provisions, the offeror may identify the provision by paragraph identifier and provide the appropriate information with its quotation or offer. Also, the full text of a solicitation provision may be accessed electronically at this/these address(es): https://www.acquisition.gov/ https://www.hhs.gov/grants-contracts/contracts/contract-policies-regulations/hhsar/part-352-solicitation-provisions-contract-clauses/index.html (End of provision) The following provisions apply to this acquisition and are incorporated by reference: FAR 52.204-7 System for Award Management (OCT 2018) FAR 52.204-16 Commercial and Government Entity Code Reporting (AUG 2020) FAR 52.211-6 Brand Name or Equal (AUG 1999) FAR 52.212-1 Instructions to Offerors—Commercial Products and Commercial Services (MAR 2023) FAR 52.212-3 Offeror Representations and Certifications—Commercial Products and Commercial Services (DEC 2022) FAR 52.214-34 Submission of Offers in the English Language (APR 1991) FAR 52.214-35 Submission of Offers in U.S. Currency (APR 1991) FAR 52.222-22 Previous Contracts and Compliance Reports (FEB 1999) FAR 52.225-4 Buy American-Free Trade Agreements-Israeli Trade Act Certificate (OCT 2022)-Alternate II (DEC 2022) FAR 52.225-25 Prohibition on Contracting With Entities Engaging in Certain Activities or Transactions Relating to Iran—Representation and Certifications (JUN 2020) HHSAR 352.239-73, Electronic and Information Technology Accessibility Notice (December 18, 2015) – included in full text (See Attachment 2) FAR 52.252-2 Clauses Incorporated by Reference (FEB 1998) This contract incorporates one or more clauses by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. Also, the full text of a clause may be accessed electronically at this/these address(es): https://www.acquisition.gov/ https://www.hhs.gov/grants-contracts/contracts/contract-policies-regulations/hhsar/part-352-solicitation-provisions-contract-clauses/index.html (End of clause) The following clauses apply to this acquisition and are incorporated by reference (IBR): FAR 52.204-13, System for Award Management Maintenance (OCT 2018) FAR 52.204-18, Commercial and Government Entity Code Maintenance (AUG 2020) FAR 52.212-4 Contract Terms and Conditions—Commercial Products and Commercial Services (DEC 2022). Addendum to this FAR clause applies to this acquisition and is attached. FAR 52.225-3 Buy American-Free Trade Agreements-Israeli Trade Act (DEC 2022)-Alternate II (Dec 2022) HHSAR 352.222-70, Contractor Cooperation in Equal Employment Opportunity Investigations (December 18, 2015) (See Attachment 2) HHSAR 352.239-74, Electronic and Information Technology Accessibility (December 18, 2015) (See Attachment 2) The following provisions and clauses apply to this acquisition and are attached in full text. Offerors MUST complete the provisions at 52.204-24 and 52.204-26 in accordance with FAR 4.2103 Procedures and submit with its quotation. FAR 52.204-24 Representation Regarding Certain Telecommunications and Video Surveillance Services or Equipment (Nov 2021) (See Attachment 2) FAR 52.204-26 Covered Telecommunications Equipment or Services-Representation (Oct 2020) (See Attachment 2) FAR 52.212-5 Contract Terms and Conditions Required To Implement Statutes or Executive Orders—Commercial Products and Commercial Services (MAR 2023) (See Attachment 3) NIH Invoice and Payment Provisions with IPP (Updated 4/21/2022) (See Attachment 4) (ix) The provision at FAR 52.212-2 Evaluation—Commercial Products and Commercial Services (NOV 2021), applies to this acquisition. (a) The Government will award a purchase order resulting from this solicitation on the basis of lowest price technically acceptable. Technical acceptability will be evaluated based upon the following: The Offeror must include all brand name (Thermo Fisher Scientific Falcon 4i Direct Electron Detector) or equal equipment detailed in the purchase description in its quotation. Or Equal equipment must meet or exceed each salient characteristic in the purchase description and in the table below. Salient characteristics: The salient physical, functional, or performance characteristics that “equal” products must meet are as follows: 1. Have the functionality to search for a high-speed, over 300 internal frames persecond and with a minimum overhead time (< 1 second) to ensure more data in a unit time. Yes/No: _________________ Comment/Reference: ____________ 2. Have a large physical pixel size of 14?m to enable DQR to remain unsurpassed over the entire spatial frequency range. Yes/No: _________________ Comment/Reference: ____________ 3. Store full temporal (310 frames per second stored on a disk without a file size penalty) and spatial (true super-resolution up to 16kX16k information is available without a file size penalty, yielding improved DQE at physical Nyquist) resolution for data collection and storage or convert directly into dose-fractions for storage in traditional MRC or LZW TIFF images. Yes/No: _________________ Comment/Reference: ____________ 4. Be compatible with Thermo Scientific data acquisition software packages (EPU&Tomography) and Data Management Platform (DMP). Yes/No: _________________ Comment/Reference: ____________ 5. Be compatible with 3rd-party software via Advanced TEM Scripting, which allows the 3rd-party software to develop more sophisticated program to control the scope and camera for specific data collection. Yes/No: _________________ Comment/Reference: ____________ In addition to completing the table above, the respondents must provide brochures and/or published technical specifications that provide evidence of or equal equipment’s ability to meet the specifications in the table above. (b) Options. – Not applicable and will not be evaluated. (c) A written notice of award or acceptance of an offer, mailed or otherwise furnished to the successful offeror within the time for acceptance specified in the offer, shall result in a binding contract without further action by either party. Before the offer’s specified expiration time, the Government may accept an offer (or part of an offer), whether or not there are negotiations after its receipt, unless a written notice of withdrawal is received before award. (End of provision) (x) Offerors shall include a completed copy of the provision at FAR 52.212-3 Offeror Representations and Certifications—Commercial Products and Commercial Services (DEC 2022), with its offer. If the offeror has completed FAR clause 52.212-3 at www.sam.gov, then the offeror does not need to provide a completed copy with its offer. (xi) The clause at FAR 52.212-4 Contract Terms and Conditions—Commercial Products and Commercial Services (DEC 2022), applies to this acquisition and is incorporated by reference. Addendum to this FAR clause applies to this acquisition and is attached (Attachment 2). (xii) There are no additional contract requirement(s) or terms and conditions applicable to this acquisition. (xiii) The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. (xiv) Responses to this solicitation must include sufficient information to establish the interested parties’ bona-fide capabilities of providing the product or service. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s), product description, and any other information or factors that may be considered in the award decision. Such factors may include: past performance, special features required for effective program performance, trade-in considerations, probable life of the item selected as compared with that of a comparable item, warranty considerations, maintenance availability, and environmental and energy efficiency considerations. Respondents proposing on an equal product of the brand-name product specified in this announcement must provide, as part of their response: (a) product, catalog, model, and/or part number(s); (b) product description; (c) all relevant information and documentation that the item(s) offered meets the salient physical, functional, or performance characteristics as specified in the purchase description; quantity; estimated price or cost; shipping, handling, and/or installation charges; and delivery date after receipt of order. The Unique Entity ID from SAM.gov, the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. All quotations must be received by 4:00 p.m., Eastern Daylight/Standard Time, on Wednesday, June 7, 2023, and reference Solicitation Number 75N95023Q00079. Responses must be submitted electronically to Cassandra Conley, Contract Specialist, at cassandra.conley@nih.gov. Fax responses will not be accepted. For information regarding this solicitation, please contact the Contract Specialist at cassandra.conley@nih.gov. Attachments: Attachment 1 Purchase Description Attachment 2 Additional Terms and Conditions Attachment 3 FAR 52.212-5 Contract Terms and Conditions Required To Implement Statutes or Executive Orders—Commercial Products and Commercial Services (MAR 2023) Attachment 4 NIH Invoice and Payment Provisions with IPP (Updated 4/21/2022)

Inactive

This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capabil... This is a Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement. This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement, to determine the method of acquisition, and availability of domestic sources manufactured in the United States in sufficient and reasonably available commercial quantities and of a satisfactory quality. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. Small businesses are encouraged to respond. For equipment/supply requirements, responses must include the place of manufacturing (i.e. address if supply/equipment is a domestic end product and include country of manufacture). For equipment/supply requirements, small businesses must also address the size status of the manufacturer under the applicable NAICS code (i.e. address Non-Manufacturer Rule). Background: Upgrading the Falcon 4 Electron Detector to the 4i and the Data Management Platform (DMP) to DMP2 can increase data collection speed by up to 25%. Purpose and Objectives: Our objective is to upgrade the Falcon 4 Electron Detector to 4i and DMP upgrade to DMP2. Project requirements: Falcon 4i benefits from an increased internal frame rate (320fps) and significantly reduced overhead time (reduced to 0.5 seconds per acquisition). Thanks to its large (14 ?m) pixel size and lowest noise levels, Falcon 4i’s (electron counting) DQE remains unsurpassed over the entire spatial frequency range, enabling highest quality 3D structures of even the most challenging (small and flexible) biological samples. Falcon 4i’s native file format is EER (electron event representation) which offers users the option to store full temporal and spatial (super) resolution or convert directly into dose-fractions for storage in traditional MRC or LZW TIFF images. Data in EER format benefit from: - Full temporal resolution: 310 frames per second are stored on disk without a file size penalty. No fractionation is required at the time of acquisition. Instead, fractionation decisions can be applied during the data processing, when the full insight in the acquired data is available. - Full spatial resolution: true super-resolution up to 16k x 16k information is available without a file size penalty, yielding improved DQE at physical Nyquist. - EER files can be read directly by the leading data processing packages. Algorithms and code to decompress and decode EER files are available publicly and free of charge. Falcon 4i is fully integrated in Thermo Scientific data acquisition software packages (EPU & Tomography) and the Data Management Platform (DMP). Selected specifications Falcon 4i 200 and 300kV * Sensor size = 4,096 x 4,096 pixels, 5.7 x 5.7 cm2 * Internal frame rate = 320 fps * Frame rate to storage = 310 fps (EER mode) * Camera overhead time = 0.5 s per acquisition * File formats = EER (native), MRC, LZW TIFF * Automation = Integrated in EPU and Tomography software Compatible with 3rd-party software via Advanced TEM Scripting Imaging performance in EER mode (see note 1): DQE(0) = 0.92 (300kV) or 0.85 (200kV), DQE(½ Nyquist) = 0.72 (300kV) or 0.60 (200kV), DQE(1 Nyquist) = 0.50 (300kV) or 0.20 (200kV) Note 1: For each sensor, DQE at a dose rate of 2 e/p/s is guaranteed by factory validation; this measurement will not be repeated on-site. DQE measurements at higher dose rates typically overestimate DQE due to non-linear behavior. System Requirements / pre-conditions: - Falcon 4 or Selectris w/ Falcon 4 already installed - 300kV or 200kV FEG TEM with control software version 3.10 or 2.10 respectively - Data Management Platform (DMP2) is required; if not present, it needs to be ordered separately. Anticipated period of performance: 30 days After Receipt of Order (ARO) Other important considerations: In case domestic sources are available and capable of fulfilling the Government’s need, and a future solicitation is published, the Government will use evaluation preferences in accordance with FAR 25. Capability statement /information sought. Companies that believe they possess the capabilities to provide the required products should submit documentation of their ability to meet each of the project requirements to the Contracting Officer. The capability statement must specifically address each of the project requirements separately. Additionally, the capability statement should include 1) the total number of employees, 2) the professional qualifications of personnel as it relates to the requirements outlined, 3) any contractor GSA Schedule contracts and/or other government-wide acquisition contracts (GWACs) by which all of the requirements may be met, if applicable, and 4) any other information considered relevant to this program. Capability statements must also include the Company Name, Unique Entity ID from SAM.gov, Physical Address, and Point of Contact Information. The response must include the respondents’ technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses. Interested companies are required to identify their type of business, applicable North American Industry Classification System (NAICS) Code, and size standards in accordance with the Small Business Administration. The government requests that no proprietary or confidential business data be submitted in a response to this notice. However, responses that indicate the information therein is proprietary will be properly safeguarded for Government use only. Capability statements must include the name and telephone number of a point of contact having authority and knowledge to discuss responses with Government representatives. Capability statements in response to this market survey that do not provide sufficient information for evaluation will be considered non-responsive. When submitting this information, please reference the solicitation notice number. One (1) copy of the response is required and must be in Microsoft Word or Adobe PDF format using 11-point or 12-point font, 8-1/2” x 11” paper size, with 1” top, bottom, left and right margins, and with single or double spacing. The information submitted must be in and outline format that addresses each of the elements of the project requirement and in the capability statement /information sought paragraphs stated herein. A cover page and an executive summary may be included but is not required. The response is limited to ten (10) page limit. The 10-page limit does not include the cover page, executive summary, or references, if requested. All responses to this notice must be submitted electronically to the Contract Specialist and Contracting Officer. Facsimile responses are NOT accepted. The response must be submitted to Cassandra Conley, Contract Specialist, at e-mail address Cassandra.conley@nih.gov. The response must be received on or before February 3rd at 12 pm, Eastern Time. Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization’s qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a presolicitation synopsis and solicitation may be published in www.sam.gov. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).