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SAM.gov SOURCES SOUGHT NOTICE Solicitation Number: 75N95022Q00333 Title: BlueCatBio BlueBench System Purchase – Antiviral Program for Pandemics Classification Code: 6640 -- LABORATORY EQUIPMENT AND SU... SAM.gov SOURCES SOUGHT NOTICE Solicitation Number: 75N95022Q00333 Title: BlueCatBio BlueBench System Purchase – Antiviral Program for Pandemics Classification Code: 6640 -- LABORATORY EQUIPMENT AND SUPPLIES NAICS Code: 334516 Description: ANALYTICAL LABORATORY INSTRUMENT MANUFACTURING This is a Sources Sought Notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding the availability and capability of all qualified sources to perform a potential requirement. This notice is issued to help determine the availability of qualified companies technically capable of meeting the Government requirement and to determine the method of acquisition. It is not to be construed as a commitment by the Government to issue a solicitation or ultimately award a contract. Responses will not be considered as proposals or quotes. No award will be made as a result of this notice. The Government will NOT be responsible for any costs incurred by the respondents to this notice. This notice is strictly for research and information purposes only. Background: The Antiviral Program for Pandemics (APP) is an initiative that seeks to accelerate antiviral development through early discovery and pre-clinical development of safe and effective oral antivirals. The initial priority for the APP is to develop treatments for SARS-CoV-2 and other coronaviruses, with the program expanding to address other virus families with pandemic potential. NCATS will apply its proficiency in drug discovery and development and its cutting-edge technologies to fill critical needs of the APP, such as (i) target validation, (ii) high-throughput screening (HTS) for drug starting points, (iii) medicinal chemistry for lead optimization, and (iv) preclinical, investigational new drug (IND)-enabling development. APP chemists within DPI are tasked with the discovery and development potential small molecule antiviral treatments for a range of viruses that have pandemic potential. In order to meet the increased demand for sample purification and analysis, the Antiviral Program for Pandemics (APP) needs to rely on instrumentation that can handle throughput of experimentation, as well as help accelerate the discovery chemistry rate in the laboratory. APP currently owns a BlueWasher. an automated, centrifugation-based plate washer with dispenser system. The requested equipment is a BlueBench that will interface with the existing BlueWasher and provide automation for the washer. This instrument will enable NCATS researchers to gently wash microplates using centrifugation, which will greatly increase the throughput of ELISA based assays, and other assays that require multiple wash steps. Centrifugation allows for a contact-free and complete removal of liquid from the well without disrupting adherent cells. High-throughput screening projects require the washing of 384- and 1536-well microplates. One of NCATS’ goals is to develop methods that advance the science of High-throughput screening and informatics by addressing the high incidence of false-positives in target discovery. To this end, it is imperative that errors are reduced as much as possible. The BlueWasher reduces noise in many phenotypic screens we are running as part of our research screenings. Overall this project will support ongoing work for small molecule and combination screening, in silico virtual screening, nanobody/antibody design and optimization that are part of NCATS’s ongoing work to support the pandemic response. Purpose and Objectives: The purpose of this procurement is the acquisition of a BlueCatBio BlueBench System for the Antiviral Program for Pandemics (APP) within the Division of Pre-clinical Innovation (DPI) at NCATS. Project requirements: The requested goods consist of the following BlueCatBio brand equipment: BlueBench, Quantity 1. 12 month warranty Shipping and handling Anticipated period of performance: One-time delivery. Number of days after receipt of order is TBD. Requested Response: The intent of this sources sought notice is to define the procurement strategy (e.g. set-aside, sole source, unrestricted) for a solicitation that is intended to be posted soon. Interested contractors are requested to respond by (1) identifying how their proposed product meets or exceeds the project requirements listed above; and (2) providing product literature, white papers, or capability statements that demonstrate their bona fide ability to supply such an item within the time frame described above. In addition, please state your business size status and whether you are the manufacturer or authorized distributor of the item you propose. Please note that NCATS is particularly interested in small business sources. If you are a small business, please state the type of small business (small business; HUBZone; service-disabled, veteran-owned; 8(a); veteran-owned; woman-owned; or small disadvantaged businesses) and your size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. The respondent must also provide their DUNS number, organization name, address, point of contact, and size and type of business (e.g., 8(a), HubZone, etc.), pursuant to the applicable NAICS code and any other information that may be helpful in developing or finalizing the acquisition requirements. The information submitted must be must be in an outline format that addresses each of the elements of the project requirements and in the capability statement /information sought paragraphs stated herein. A cover page and an executive summary may be included but is not required. The response must include the respondents’ technical and administrative points of contact, including names, titles, addresses, telephone and fax numbers, and e-mail addresses. All responses to this notice must be submitted electronically to the Contracting Officer. Facsimile responses are NOT accepted. The response must be submitted to Kevin Alvarez, Contracting Officer, at e-mail address kevin.alvarez@nih.gov. The response must be received on or before July 5, 2022, 9:00am, Eastern Time. Disclaimer and Important Notes: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization’s qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After a review of the responses received, a presolicitation synopsis and solicitation may be published at SAM.gov. However, responses to this notice will not be considered adequate responses to a solicitation. Confidentiality: No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use any non-proprietary technical information in any resultant solicitation(s).