Inactive

COMPETITIVE COMBINED SYNOPSIS / SOLICITATION Title: Brand-Name Biotage V-10 Touch System or equal to the Biotage V-10 Touch System/Automated Laboratory Evaporator RFQ: 75N95022Q00121 (i) This is a com... COMPETITIVE COMBINED SYNOPSIS / SOLICITATION Title: Brand-Name Biotage V-10 Touch System or equal to the Biotage V-10 Touch System/Automated Laboratory Evaporator RFQ: 75N95022Q00121 (i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; proposals are being requested and a written solicitation will not be issued. (ii) The solicitation number is 75N95022Q00121 and the solicitation is issued as a request for quotation (RFQ). This acquisition is for a commercial item and is conducted under the authority of the Federal Acquisition Regulation (FAR) Part 13—Simplified Acquisition Procedures; and FAR Part 12—Acquisition of Commercial Items, and is not expected to exceed the simplified acquisition threshold. (iii) The solicitation document and incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) Number 2022-02, with effective date January 14, 2022 (iv) The associated NAICS code 334516 and the small business size standard 1,000 employees. This requirement is set-aside for small business. DESCRIPTION (v) As NCATS is making progress in adapting some of the goals outlined in the Automated Synthesis Platform for Innovative Research and Execution (ASPIRE) initiative, a significant effort has been spent in identifying gaps in our medicinal chemistry labs that need to be filled in order for automation to be successful. Currently, we have a system that can evaporate high boiling solvents generated by various chemistry processes from multiple samples in automation. Evaporative systems such as the Biotage® V-10 Touch rapidly dry samples dissolved in both aqueous and organic solvents. It easily evaporates HPLC fractions from purification rapidly and can do this in automation. It can be utilized to dry-down compounds onto silica for easier dry load capabilities prior to purification with silica gel chromatography. It also removes high boiling point organic solvents such as DMSO (or DMF or NMP) in minutes from synthesis; it can also recover small samples of compounds after acquiring NMR spectra in DMSO. Besides speed, the advantage over blow-down units that we currently have is that the evaporation can be done without increasing the temperature of the sample. The rapid turnaround time will enable rapid sequential same-day multistep synthesis with quick isolation and identification of intermediate. As our workload has increased exponentially, we find we have need of a second evaporator unit to avoid bottlenecks in workflow. (vi) Generic Name of Product: Automated Laboratory Evaporator Purchase Description: For reference purposes, the normal phase flash purifications chromatography system with automated mass directed fraction collection that meets the need of this requirement is the Brand-Name Biotage V-10 Touch System described below: Part Number (PN) QTD Description V-10-2xx 1 V-10 Touch System 414865 1 V-10 Solvent Manager Upgrade 411816 1 Gilson Liquid Handler GX271 – V10 414867 1 Kit, Start-Up for Liquid Handlers, V-10 Touch 416009SP 1 Hi-vac, oil free scroll pump, 100-240V 413146 1 External vacuum pump connection kit for Vaccubrand and Edwards hi-vac. pumps 415082 1 110/120-230 VAC Step-up Transformer SER-V10-FYMP 1 First Year Maintenance Package – Biotage® V-10 The salient physical, functional, or performance characteristics that “equal” products must meet are as follows: • Automated laboratory evaporator system • Walk-up, walk-away capability • Does not require liquid-liquid extraction steps • Removes high boiling point solvents (e.g. water, DMSO, DMF, NMP) from organic samples typically generated in medicinal chemistry laboratories using vacuum at ambient temperatures. • The system must be capable of automatically evaporating solvents in parallel or sequentially from multiple samples. • The system must have the adaptability to use its evaporative technology to remove solvents from an HPLC rack of test tubes or from a flask with a high volume of solvent in automation. • Capable of removing small samples of compounds after acquiring NMR spectra in DMSO. • Provides same-day multistep synthesis • Fully equal in capabilities (capacity, speed, integration with existing control and automation systems) as the currently installed Biotage V-10 Touch System, which includes the V-10 Solvent Manager upgrade and Gilson Liquid Handler. • Footprint not to exceed 15.7”W x 19”D x 21”D • Must have double trapping exhaust • Must have a heating range of 20-70°C • Must be able to handle speed of 3000 – 8000 RPM • Shipping and Handling. (vii) The Government anticipates award of a firm fixed-price purchase order for this acquisition, and the anticipated delivery date is within 90 (ninety) days after receipt of order (ARO). The exact date and time of installation and training shall be coordinated with the NCATS Point of Contact listed on the purchase order. Delivery shall be made to the below address with FOB Destination. National Center for Advancing Translational Sciences (NCATS) 9800 Medical Center Drive Rockville, MD 20850 TERMS AND CONDITIONS, PROVISIONS, AND REPRESENTATIONS (viii) The provision at FAR 52.252-1, Solicitation Provisions Incorporated by Reference (Feb 1998), applies to this acquisition. This solicitation incorporates one or more solicitation provisions by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. The offeror is cautioned that the listed provisions may include blocks that must be completed by the offeror and submitted with its quotation or offer. In lieu of submitting the full text of those provisions, the offeror may identify the provision by paragraph identifier and provide the appropriate information with its quotation or offer. Also, the full text of a solicitation provision may be accessed electronically at these addresses: https://www.acquisition.gov/browse/index/far https://www.hhs.gov/grants/contracts/contract-policies-regulations/hhsar/index.html (End of provision) The following provisions apply to this acquisition and are incorporated by reference: • FAR 52.204-7, System for Award Management (Oct 2018) • FAR 52.204-16, Commercial and Government Entity Code Reporting (Aug 2020) • FAR 52.204-24 Representation Regarding Certain Telecommunications and Video Surveillance Services or Equipment (Oct 2020) • FAR 52.204-26 Covered Telecommunications Equipment or Services- Representation (Oct 2020) • FAR 52.211-6, Brand Name or Equal (Aug 1999) • FAR 52.212-1, Instructions to Offerors-Commercial Items (Jun 2020) • FAR 52.212-3, Offeror Representations and Certifications-Commercial Items (Feb 2021) • FAR 52.225-2, Buy American Certificate (Feb 2021) • FAR 52.225-4, Buy American-Free Trade Agreements-Israel Trade Act Certificate (Feb 2021) • FAR52.225-6, Trade Agreements Certificate (Feb 2021) • HHSAR 352.239-73, Electronic and Information Technology Accessibility Notice (December 18, 2015) The clause at FAR 52.252-2, Clauses Incorporated by Reference (Feb 1998), applies to this acquisition. This contract incorporates one or more clauses by reference, with the same force and effect as if they were given in full text. Upon request, the Contracting Officer will make their full text available. Also, the full text of a clause may be accessed electronically at these addresses: https://www.acquisition.gov/browse/index/far https://www.hhs.gov/grants/contracts/contract-policies-regulations/hhsar/index.html (End of clause) The following clauses apply to this acquisition and are incorporated by reference: • FAR 52.204-13, System for Award Management Maintenance (Oct 2018) • FAR 52.204-18, Commercial and Government Entity Code Maintenance (Aug 2020) • FAR 52.212-4, Contract Terms and Conditions--Commercial Items (Oct 2018) • HHSAR 352.239-74, Electronic and Information Technology Accessibility (December 18, 2015) (ix) Offerors are to include a completed copy of the provision at FAR clause 52.212-3, Offeror Representations and Certifications—Commercial Items (Feb 2021), with offers. (x) The clause at FAR 52.212-4, Contract Terms and Conditions-Commercial Items (Oct 2018), applies to this acquisition. Addendum to this FAR clause applies to this acquisition and is attached. • FAR 52.212-4 Addendum – Supplier License Agreements, attached. • FAR 52.212-4(g), Invoice, is supplemented by: o NIH Invoice and Payment Instructions (Feb 2021) (xi) The clause at FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders-Commercial Items (Jan 2021), applies to this acquisition and is attached in full text. (xii) Please include manufacture warranty provisions. (xiii) The Defense Priorities and Allocations System (DPAS) are not applicable to this requirement. EVALUATION (xiv) The Government may perform a comparative evaluation of responses in accordance with FAR 13.106-2(b) to select the contractor that is best suited and provides the best value, considering the evaluation factors in this solicitation. The evaluation will compare: Technical capability of the item offered to meet the Government requirement in accordance with the salient characteristics specified in the Purchase Description, Price, and Past Performance as defined under FAR 13.106-2(b)(3). If only one quotation is received it will be evaluated on the preceding. The government reserves the right to select a response that provides benefit to the government that exceeds the minimum; the government is not required to select a response that exceeds the minimum; responses may exceed the requirements; each response must meet the solicitation requirement statement at a minimum; and the government is not requesting or accepting alternate proposal(s) SUBMISSION INSTRUCTIONS (xv) Responses to this solicitation must include sufficient information to establish the interested parties’ bona-fide capabilities of providing the product. The price quote shall include: unit price, list price, shipping and handling costs, delivery days after contract award, delivery terms, prompt payment discount terms, F.O.B. Point (Destination or Origin), product or catalog number(s), product description, and any other information or factors that may be considered in the award decision. Such factors may include: past performance, special features required for effective program performance, trade-in considerations, probable life of the item selected as compared with that of a comparable item, warranty considerations, maintenance availability, and environmental and energy efficiency considerations. Respondents proposing on an equal product of the brand-name product specified in this announcement must provide, as part of their response: (a) product, catalog, model, and/or part number(s); (b) product description; (c) all relevant information and documentation that the item(s) offered meets the salient physical, functional, or performance characteristics as specified in the purchase description; quantity; estimated price or cost; shipping, handling, and/or installation charges; and delivery date after receipt of order Dun & Bradstreet Number (DUNS), the Taxpayer Identification Number (TIN), and the certification of business size must be included in the response. All offerors must have an active registration in the System for Award Management (SAM) www.sam.gov. All questions must be received by 11:00 a.m., Eastern Time, on February 28, 2022 and reference Solicitation Number 75N95022Q00121. Responses must be submitted by email to Michelle Cecilia, Contract Specialist, michelle.cecilia@nih.gov, tel. (301) 451- 2596. All quotations must be received by 11:00 a.m., Eastern Time, on March 3, 2022 and reference Solicitation Number 75N95022Q00121. Responses must be submitted by email to Michelle Cecilia, Contract Specialist michelle.cecilia@nih.gov, tel. (301) 827-7199. Fax responses will not be accepted. (xvi) The name and telephone number of the individual to contact for information regarding the solicitation: Michelle Cecilia Contract Specialist Phone: (301) 827-7199 Email: michelle.cecilia@nih.gov ATTACHMENTS (xvii) Attachments: - FAR 52.204-24, Representation Regarding Certain Telecommunications and Video Surveillance Services or Equipment (Nov 2021) - FAR 52.204-26 Covered Telecommunications Equipment or Services- Representation (Oct 2020) - FAR 52.212-4 Addendum – Supplier License Agreements (Nov 2021) - FAR 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders–Commercial Items (Jan 2022) - FAR 52.225-2, Buy American Certificate (Feb 2021) - NIH Invoice and Payment Provisions (Feb 2021) - HHSAR 352.232-71 Electronic Submission of Payment Requests (February 2, 2022)