Inactive

Tox21 collaboration between NCATS (then NCGC), NTP, EPA and FDA started with an aim to screen tens of thousands of known drugs and compounds in vitro by reducing the cost and time consuming processes ... Tox21 collaboration between NCATS (then NCGC), NTP, EPA and FDA started with an aim to screen tens of thousands of known drugs and compounds in vitro by reducing the cost and time consuming processes involved in traditional toxiciticy testing methods. Since its inception nearly a decade ago, several screenings against Tox21 compound collection were performed at NCATS by running cell-based assays focused mainly on different targets and toxicity pathways which included nuclear receptor signaling, stress response, and developmental toxicology etc. Most of these assays have a beta-lactamase reporter gene construct. In order to quanitfy the induction/inhibiton of these reporter gene activities, LiveBlazer FRET B/G loading dye will be used. This procurement is for LiveBlazer FRET B/G loading, 5mg -- Catalog # K1030. Quantity 10ea. Please see attached combined synopsis/solicitation for full details