Inactive

The National Heart, Lung, and Blood Institute (NHLBI) Office of Acquisition (OA) on behalf of the National Human Genome Research Institute, (NHGRI), intends to negotiate and award a purchase order on ... The National Heart, Lung, and Blood Institute (NHLBI) Office of Acquisition (OA) on behalf of the National Human Genome Research Institute, (NHGRI), intends to negotiate and award a purchase order on a non-competitive sole source basis without providing for full and open competition to Metabolon, 617 Davis Dr., Suite 400, Morrisville, North Carolina 27560-7171. The purpose of the procurement is to study global metabolomics plus Short Chain Fatty Acid (SCFAs) panel in serum samples of diabetic and non-diabetic individuals of African descent. A subset of the cohort (e.g., East Africans) also has an unexpectedly high circulating triglycerides compared to levels reported in other African populations. Therefore, a secondary objective of this procurement is to compare the metabolic profile of individuals with high triglyceride levels to those with low level of triglycerides. With foresight towards integrating multiple omics analyses in these individuals using outcomes such as metabolic phenotypes including anthropometric markers or clinical biomarkers ascertained during their initial assessment through the Africa America Diabetes study (AADM).