The Persistent Organic Pollutant (POP) group at the Arkansas Human and Animal Food Laboratory (ARHAFL) requires a dedicated ultra-high-performance liquid chromatography (UHPLC) system for PFAS analysis. This system will support a method transfer and shared utilization of a Thermo Q Exactive HF mass spectrometer with the Chemotherapeutics group. The dedicated UHPLC is needed to minimize cross-contamination and reduce setup time between instrument swaps. The work is performed at ARHAFL in Arkansas.