Inactive Total Small Business Set-Aside (FAR 19.5)

The Ultrasound Program within the Division of Applied Mechanics (DAM), Office of Science and Engineering Laboratories (OSEL), Center for Devices and Radiological Health (CDRH), and the U.S. Food and D... The Ultrasound Program within the Division of Applied Mechanics (DAM), Office of Science and Engineering Laboratories (OSEL), Center for Devices and Radiological Health (CDRH), and the U.S. Food and Drug Administration (FDA) would like to purchase a state-of-the-art, tomographic microscope to: (i) characterize the behavior of cells, single and populations of cells, and cells in static and flow-based conditions before, during, and after ultrasound treatments, (ii) simulate flows in the ibidi compatible devices for the vasculature- and neuro-systems, (iii) study bubble collapse dynamics affects for ultrasound applications, such as the opening the Blood-Brain Barrier, neuromodulation, or ablation of tissue, and (iv) evaluate the interactions between physiological static and flows for ultrasound medical procedures. This equipment will help CDRH understand complex cellular mechanics and device- and treatment-related complications in the ultrasound diagnostic and therapeutic spaces.