The National Institutes of Health (NIH) Clinical Center in Bethesda, MD intends to award a sole source contract to ACROBiosystems Inc. for fifteen vials of GMP-grade Human Interleukin-2 (IL-2) protein. This product is required to support FDA-regulated cell and gene therapy manufacturing at the Center for Cellular Engineering, where it has already been validated for use. Substituting another manufacturer’s product would require extensive process revalidation, causing significant cost increases and delays that could interrupt patient treatment. The place of performance is the NIH Clinical Center in Bethesda, MD 20892. No budget amount or submission timeline is specified, as this is a notice of intent to award a sole source contract, not a request for competitive quotes.