The National Institutes of Health intends to award a sole-source, firm-fixed-price contract to the University of Maryland Baltimore for Option Year 4 of the "Getting to Zero HIV Transmission Through Enhanced LEN for PrEP (HELP) Study." The performance period is one year with an anticipated effective date of September 15, 2026. Services include designing an adaptive intervention for LEN adherence and retention, establishing three study nodes in Washington, DC, Baltimore, and West Virginia, and supporting a five-year multicenter implementation trial. This is a notice of intent, not a request for quotes. Interested parties may submit a capability statement for consideration.