Lawrence Berkeley National Laboratory’s Molecular Foundry Division operates a DOE Office of Science User Facility offering state-of-the-art expertise and instrumentation for nanoscale science research across materials science, chemistry, biology, and energy. A dedicated Micro Electron Diffractometer (MicroED) System supports this mission by enabling routine atomic-structure determination for nanocrystalline and microcrystalline materials too small for conventional single-crystal X-ray diffraction. This capability ensures advanced structural characterization for user projects and scientific discoveries meets the facility’s demanding research standards.