MTEC is pre-announcing an upcoming Request for Project Proposals for medical prototype solutions across 15 focus areas, including prevention of harmful behaviors, infectious diseases, trauma infections, pain management, and blast exposure monitoring. Each proposal must address only one focus area, and solutions must meet the prototype definition with a minimum KRL/TRL of 3, be new to MTEC, and have preliminary data. The acquisition will use an Enhanced White Paper approach, with Stage 1 white papers from MTEC members and selected offerors invited to submit Stage 2 cost proposals. Funding is contingent on federal availability, with average MTEC awards of approximately $2.0–3.5M over a 2–3 year period of performance, and potential non-competitive follow-on tasks may be awarded based on project success. Teaming is encouraged but not required.