DARPA is seeking innovative approaches to develop continuously updating digital twin models of the cardiovascular system that integrate patient data and biological physics for real-time simulation and outcome prediction of medical interventions. The program aims to establish a foundation for prediction-driven decision support in medicine, shifting care from reactive to anticipatory. This capability is intended to improve clinical outcomes in acute, chronic, and emergent settings.

DARPA is seeking innovative approaches to create continuously updating digital twin models of the cardiovascular system, which would simulate interventions in real time to predict outcomes before actual patient procedures. The VITAL program aims to establish a foundation for predictive, causal decision support in medicine. This capability is intended to shift medical care from reactive to anticipatory, potentially improving outcomes in acute, chronic, and emergent clinical settings. No specific budget, performance location, or non-bid/proposal timelines are detailed in this description.