Inactive

The Macromolecular Structure and Function (MSF) Group in the Biochemical Science Division of the Materials Measurement Laboratory at the National Institute of Standards and Technology (NIST) advances ... The Macromolecular Structure and Function (MSF) Group in the Biochemical Science Division of the Materials Measurement Laboratory at the National Institute of Standards and Technology (NIST) advances novel measurement methods and models for the determination and analysis of the structure and function of biological macromolecules, including lipids, DNA, RNA, proteins, and macromolecular complexes and assemblies formed by these molecules; advancing methods to determine the physical and chemical factors which determine the specific interactions of macromolecules with cofactors and ligands; studies the relationships between biomolecular structure, dynamics, function, and energetics using computational, biophysical, and biochemical techniques; develops reference databases for these properties; and advances measurement methods for engineering complex biological systems. The Biomolecular Labeling Laboratory supports MSF and other NIST and external users by providing biomolecules labeled with stable isotopes for structural and biophysical studies. The BL2 is in need for isotopically labeled chemical to support these efforts. The labeled chemicals will be used to produce proteins labeled with stable isotopes. Reference the attached document for the complete solicitation.